T Cell Antigen Connector
July 6, 2023 ⚊ 1 Min read ⚊ Views 83 ⚊ TECH
TAC consists of multiple protein domains: (1) The antigen-binding region, (2) The TCR-CD3 complex region, and (3) The native TCR-recruitment region (including hinge, transmembrane, and cytosolic regions). TAC binds to tumor targets and co-receptor integration and leads to the natural activation of TCR signaling pathways, resulting in T-cell-mediated tumor cell killing.
Tags: T Cell
